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N6-methyladenosine




Description

   A methyladenosine compound with one methyl group attached to N6 of the adenine nucleobase.

Basic Information

Comman Name N6-methyladenosine
Symbol m6A
Chemical Formula C11H15N5O4
Nucleoside Mass 281.27

Locations and Contents

ModificationOrganisms or CellsContentsReferences
m6AHomo sapiens0.1-0.6% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/1187339/
m6AHomo sapiens0.1-0.6% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/164293/
m6AHomo sapiens0.1-0.6% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/1168101/
m6AHomo sapiens0.1-0.6% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/23177736/
m6AHomo sapiens0.1-0.6% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/22002720/
m6AHomo sapiens0.1-0.6% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/26863196/
m6AHomo sapiens1.2% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/23177736/
m6AMus musculus0.1-0.6% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/23177736/
m6AMus musculus0.1-0.6% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/26863196/
m6AMus musculus0.1-0.6% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/25456834/
m6AMus musculus0.1-0.6% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/24394384/
m6AMus musculus0.1-0.6% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/25569111/
m6Ameiotic Saccharomyces cerevisiae0.7-0.9% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/20421205/
m6AArabidopsis thaliana0.45-0.65% [m6A/A]https://pubmed.ncbi.nlm.nih.gov/25430002/
m6Amouse liver1.39±0.23% [m6A/G] https://pubmed.ncbi.nlm.nih.gov/24261999/
m6Amouse liver3.30±1.73% [m6A/G] https://pubmed.ncbi.nlm.nih.gov/24261999/
m6Amouse liver2.19±0.74% [m6A/G] https://pubmed.ncbi.nlm.nih.gov/24261999/
m6Amouse liver0.0001±0.0001% [m6A/G] https://pubmed.ncbi.nlm.nih.gov/24261999/
m6Amouse liver0.002±0.000% [m6A/G] https://pubmed.ncbi.nlm.nih.gov/24261999/
m6Amouse liver0.51±0.10% [m6A/G] https://pubmed.ncbi.nlm.nih.gov/24261999/
m6AA. th. cell culture20.6 [m6A/1000 tRNA molecules]https://pubmed.ncbi.nlm.nih.gov/23417961/
m6AA. th. plants14.5 [m6A/1000 tRNA molecules]https://pubmed.ncbi.nlm.nih.gov/23417961/

Modification Enzymes and Reactions

Modification Enzymes:ErmAM (Streptococcus pneumoniae)
Reference:https://pubmed.ncbi.nlm.nih.gov/9187657/

Modification Enzymes:ErmAM (Streptococcus pneumoniae)
Reference:https://pubmed.ncbi.nlm.nih.gov/3033720/

Modification Enzymes:ErmBC (Escherichia coli)
Reference:https://pubmed.ncbi.nlm.nih.gov/2832378/

Modification Enzymes:ErmC' (Bacillus subtilis)
Reference:https://pubmed.ncbi.nlm.nih.gov/7543473/

Modification Enzymes:Ime4 (Saccharomyces cerevisiae)
Reference:https://pubmed.ncbi.nlm.nih.gov/9585521/

Modification Enzymes:Ime4 (Saccharomyces cerevisiae)
Reference:https://pubmed.ncbi.nlm.nih.gov/20421205/

Modification Enzymes:METTL14 (Homo sapiens)
Reference:https://pubmed.ncbi.nlm.nih.gov/24316715/

Modification Enzymes:METTL3 (Homo sapiens)
Reference:https://pubmed.ncbi.nlm.nih.gov/24316715/

Modification Enzymes:METTL3 (Homo sapiens)
Reference:https://pubmed.ncbi.nlm.nih.gov/7748945/

Modification Enzymes:RlmF (Escherichia coli)
Reference:https://pubmed.ncbi.nlm.nih.gov/18021804/

Modification Enzymes:RlmJ (Escherichia coli)
Reference:https://pubmed.ncbi.nlm.nih.gov/23945937/

Modification Enzymes:RsmA (Escherichia coli)
Reference:https://pubmed.ncbi.nlm.nih.gov/22308031/

Modification Enzymes:RsmA (Saccharomyces cerevisiae)
Reference:https://pubmed.ncbi.nlm.nih.gov/19520088/

Modification Enzymes:RsmA (Thermus thermophilus)
Reference:https://pubmed.ncbi.nlm.nih.gov/19285505/

Modification Enzymes:TrmM (Escherichia coli)
Reference:https://pubmed.ncbi.nlm.nih.gov/19383770/