The Nucleic Acid Modification Database

N2,N2-dimethylguanosine

Description

A guanosine where the hydrogens of the amine group at C-2 are substituted by methyl groups

Basic Information

Comman Name	N2,N2-dimethylguanosine
Symbol	m²²G
Chemical Formula	C₁₂H₁₇N₅O₅
Nucleoside Mass	311.3

Locations and Contents

Modification	Organisms or Cells	Contents	References
m22G	mouse liver	3.56±0.46% [m22G/G]	https://pubmed.ncbi.nlm.nih.gov/24261999/
m22G	mouse liver	3.14±0.37% [m22G/G]	https://pubmed.ncbi.nlm.nih.gov/24261999/
m22G	mouse liver	2.14±0.52% [m22G/G]	https://pubmed.ncbi.nlm.nih.gov/24261999/
m22G	mouse liver	0.0006±0.0002% [m22G/G]	https://pubmed.ncbi.nlm.nih.gov/24261999/
m22G	mouse liver	0.40±0.07% [m22G/G]	https://pubmed.ncbi.nlm.nih.gov/24261999/
m22G	Rat liver	727-760 [pmol/AU]	https://pubmed.ncbi.nlm.nih.gov/14751792/
m22G	Beef liver	671-700 [pmol/AU]	https://pubmed.ncbi.nlm.nih.gov/14751792/
m22G	Sheep liver	762-766 [pmol/AU]	https://pubmed.ncbi.nlm.nih.gov/14751792/
m22G	Rabbit liver	636-680 [pmol/AU]	https://pubmed.ncbi.nlm.nih.gov/14751792/
m22G	A. th. cell culture	601.6 [m22G/1000 tRNA molecules]	https://pubmed.ncbi.nlm.nih.gov/23417961/
m22G	A. th. plants	607.2 [m22G/1000 tRNA molecules]	https://pubmed.ncbi.nlm.nih.gov/23417961/

Modification Enzymes and Reactions