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5-hydroxymethyluracil




Description

   A primary alcohol that is uracil bearing a hydroxymethyl substituent at the 5-position.

Basic Information

Comman Name 5-hydroxymethyluracil
Symbol 5hmU
Chemical Formula C5H6N2O3
Nucleoside Mass 142.11

Locations and Contents

ModificationOrganisms or CellsContentsReferences
5hmUWomen Breast0.00675% [5mU/T]https://pubmed.ncbi.nlm.nih.gov/11219773/
5hmUHeLa cells0.0003% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/23658232/
5hmUWM-266-4 human melanoma cells0.00034% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/23658232/
5hmUHuman brain tissues0.00039% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/23658232/
5hmUMouse brain tissues0.00083% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/23658232/
5hmUMouse skin tissues0.00064% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/23658232/
5hmUmESCs0.00005% [5hmU/dN]https://pubmed.ncbi.nlm.nih.gov/24838012/
5hmUPig liver0.00006% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/24055867/
5hmUPig brain0.00013% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/24055867/
5hmUTrypanosoma brucei0.00425% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/25078157/
5hmUHuman leukocytes0.0000492% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/25061097/
5hmUHuman Sperm0.0005209% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/25061097/
5hmUPig liver0.00002025% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUPig kidney0.00001225% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUPig brain0.00001102% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUPig thymus0.00001042% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUPig lymph nodes0.00004565% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUPig spleen0.00001765% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUPig heart0.00003614% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUPig intestine0.00006251% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUPig muscle0.00001439% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUMale Wistar rat liver0.00001439% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUMale Wistar rat kidney0.00001570% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUMale Wistar rat thymus0.00002770% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUMale Wistar rat heart0.00003045% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUMale Wistar rat intestine0.00001789% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUMale Wistar rat lung0.00001483% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/
5hmUMale Wistar rat brain0.00001090% [5mU/dN]https://pubmed.ncbi.nlm.nih.gov/26660343/

Modification Enzymes and Reactions

Modification Enzymes:AID/APOBEC
Reference:https://pubmed.ncbi.nlm.nih.gov/24055867/

Modification Enzymes:Thymidinehydroxylase
Reference:https://pubmed.ncbi.nlm.nih.gov/18729733/

Modification Enzymes:NgTET1
Reference:https://pubmed.ncbi.nlm.nih.gov/25831492/