ss



5-formylcytosine



Description
   A nucleobase analogue that is cytosine in which the hydrogen at position 5 is replaced by a formyl group.
Basic Information
Comman Name 5-formylcytosine
Symbol 5fC
Chemical Formula C5H5N3O2
Nucleoside Mass 139.11
Locations and Contents
ModificationOrganisms or CellsContentsReferences
5fCMouse embryonic stem (ES) Cells0.002% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5fCMouse embryonic stem (ES) Cells0.02% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/21721093/
5fCMouse embryonic stem (ES) Cells0.00077% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/23768208/
5fCMouse embryonic stem (ES) Cells0.00035% [5fC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5fCMouse embryonic stem (ES) Cells0.0022% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/28448110/
5fCHEK2930.00044% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5fCHEK293, Tet2 CD wild type0.16% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5fCHEK293, Tet2 CD mut0.00017% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5fCMouse brain cortex0.0016% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5fCMouse kidney0.0003% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5fCMouse lung0.00037% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5fCMouse heart0.00046% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5fCMouse pancreas0.00059% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5fCMouse liver0.00067% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5fCMouse spleen0.0012% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5fCMouse thymus0.00043% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5fCMouse ES cells treated with ascorbic acid0.00817% [5fC/dC]https://pubmed.ncbi.nlm.nih.gov/23768208/
5fCArabidopsis thaliana0.000079% [5fC/dN]https://pubmed.ncbi.nlm.nih.gov/24391970/
5fCHEK293T-Tet10.0076% [5fC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5fCHEK293T-Tet1m0.000023% [5fC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5fCHeLa cells0.000067% [5fC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5fCWM-266-40.000069% [5fC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5fCHuman brain0.00017% [5fC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5fCMouse brain0.00014% [5fC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5fCMouse skin (red head)0.00012% [5fC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5fCMouse skin (albino)0.00007% [5fC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5fCA. thaliana leaves0.00042% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5fCG. biloba leaves0.00028% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5fCP. orientalis leaves0.00047% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5fCO. sativa roots0.00037% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5fCO. sativa stems0.00022% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5fCO. sativa leaves0.00026% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5fCZ. mays leaves0.0003% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5fCZ. mays kernels0.00031% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5fCZ. mays silks0.0004% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5fCL. esculentum stems0.00044% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5fCL. esculentum leaves0.00021% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5fCHuman CRC tumor tissues0.000092% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/25675106/
5fCHuman CRC tumor-adjacent normal tissues0.000274% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/25675106/
5fC293T cells0.00045% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/26562407/
5fCHeLa cells0.00191% [5fC/dG]https://pubmed.ncbi.nlm.nih.gov/26562407/
5fCNHDF-Neo cells0.098/106 [5fC/dN]https://pubmed.ncbi.nlm.nih.gov/29190698/
5fCK562 cells0.042/106 [5fC/dN]https://pubmed.ncbi.nlm.nih.gov/29190698/
5fCMe45 cells0.044/106 [5fC/dN]https://pubmed.ncbi.nlm.nih.gov/29190698/
5fCHCT 116 cells0.082/106 [5fC/dN]https://pubmed.ncbi.nlm.nih.gov/29190698/
5fCRaji cells0.043/106 [5fC/dN]https://pubmed.ncbi.nlm.nih.gov/29190698/
5fCBL cells0.013/106 [5fC/dN]https://pubmed.ncbi.nlm.nih.gov/29190698/
5fC293T cells0.7/106 [5fC/DNA]https://pubmed.ncbi.nlm.nih.gov/28693723/
5fCHeLa cells0.2/106 [5fC/DNA]https://pubmed.ncbi.nlm.nih.gov/28693723/
5fCMCF-7 cells0.2/106 [5fC/DNA]https://pubmed.ncbi.nlm.nih.gov/28693723/
5fCRat tissues (Liver, Brain, Kidney, Lung)0.7-1.6/106 [5fC/DNA]https://pubmed.ncbi.nlm.nih.gov/28693723/
Modification Enzymes and Reactions
Modification Enzymes:TET
Reference:https://pubmed.ncbi.nlm.nih.gov/26734843/

Modification Enzymes:NgTET1
Reference:https://pubmed.ncbi.nlm.nih.gov/25831492/











The Nucleic Acid Modification Database (NAMDB)

鄂公网安备 42010602004491号

鄂ICP备2021000903号-1