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5-carboxylcytosine




Description

   A nucleobase analogue that is cytosine in which the hydrogen at position 5 is replaced by a carboxy group.

Basic Information

Comman Name 5-carboxylcytosine
Symbol 5caC
Chemical Formula C5H5N3O3
Nucleoside Mass 155.11

Locations and Contents

ModificationOrganisms or CellsContentsReferences
5caCMouse embryonic stem (ES) Cells0.0003% [5caC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5caCMouse embryonic stem (ES) Cells0.000083% [5caC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5caCMouse embryonic stem (ES) Cells0.0003% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/28448110/
5caCHEK293, Tet2 CD wild type0.052% [5caC/dC]https://pubmed.ncbi.nlm.nih.gov/21778364/
5caCArabidopsis. thaliana0.000078 [5caC/dN]https://pubmed.ncbi.nlm.nih.gov/24391970/
5caCHEK293T-Tet10.0102% [5caC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5caCHEK293T-Tet1m0.000018% [5caC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5caCHeLa cells0.000027% [5caC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5caCWM-266-40.000029% [5caC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5caCHuman brain0.000015% [5caC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5caCMouse brain0.000012% [5caC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5caCMouse skin (red head)0.000021% [5caC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5caCMouse skin (albino)0.000019% [5caC/DNA]https://pubmed.ncbi.nlm.nih.gov/23658232/
5caCA. thaliana leaves0.00034% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5caCG. biloba leaves0.00019% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5caCP. orientalis leaves0.00036% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5caCO. sativa roots0.00009% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5caCO. sativa stems0.00003% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5caCO. sativa leaves0.00002% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5caCZ. mays leaves0.00002% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5caCZ. mays kernels0.00006% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5caCZ. mays silks0.00003% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5caCL. esculentum stems0.00004% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5caCL. esculentum leaves0.00004% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/24970241/
5caCHuman CRC tumor tissues0.000009% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/25675106/
5caCHuman CRC tumor-adjacent normal tissues0.000031% [5caC/dG]https://pubmed.ncbi.nlm.nih.gov/25675106/

Modification Enzymes and Reactions

Modification Enzymes:TET
Reference:https://pubmed.ncbi.nlm.nih.gov/26734843/

Modification Enzymes:NgTET1
Reference:https://pubmed.ncbi.nlm.nih.gov/25831492/