The Nucleic Acid Modification Database

N2,3-ethenoguanine

Description

A nucleobase analogue obtained by addition of an etheno group across positions N2 and 3 of guanine.

Basic Information

Comman Name	N2,3-ethenoguanine
Symbol	N(2),3-ɛG
Chemical Formula	C7H5N5O
Nucleoside Mass	175.15

Locations and Contents

Modification

Organisms or Cells

Contents

References

Modification Enzymes and Reactions

Modification Enzymes:(i)by reaction with oxidized metabolites of vinyl chloride, 2-chloroacetaldehyde and 2-chloroethylene oxide; (ii) by endogenous processes through the interaction of lipid peroxidation (LPO)-derived aldehydes and hydroxyalkenals.

Reference:https://pubmed.ncbi.nlm.nih.gov/14637257/