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8-oxoguanine



Description
   An oxopurine that is guanine which is substituted by an oxo group at position 8.
Basic Information
Comman Name 8-oxoguanine
Symbol 8-oxo-G
Chemical Formula C5H3N5O2
Nucleoside Mass 165.11
Locations and Contents
ModificationOrganisms or CellsContentsReferences
8-oxo-GHuman leukocytes0.00033% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/2074046/
8-oxo-GCalf thymus0.06528% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/1899997/
8-oxo-GHuman brain0.00136% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/1324197/
8-oxo-GHuman lung0.00968% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/1324197/
8-oxo-GHuman colon0.00271% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/1324197/
8-oxo-GHuman stomach0.00094% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/1324197/
8-oxo-GHuman ovary0.00311% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/1324197/
8-oxo-GNon-cancerous breast tissues0.0051% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/7634251/
8-oxo-GBreast cancer tissues.0.0036% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/7634251/
8-oxo-GNormal breast tissue0.008% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/8758255/
8-oxo-GBenign tumors breast tissue0.03136% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/8758255/
8-oxo-GMalignant breast tissue0.07808% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/8758255/
8-oxo-GHuman leukocytes0.00031% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/8653695/
8-oxo-GLymphocyte0.00374% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/8917660/
8-oxo-GChildren Human lymphocytes0.008608% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/9373171/
8-oxo-GHuman lung tissue0.00052% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/9328173/
8-oxo-GLung cancer tissues0.00052% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/9738974/
8-oxo-GSquamous cell carcinoma lung tissues0.00052% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/9738974/
8-oxo-GAdenocarcinoma lung tissues0.00051% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/9738974/
8-oxo-GNormal lung tissues0.00037% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/9738974/
8-oxo-GHuman leukocytes0.0034% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/10023075/
8-oxo-GNon-cancerous breast tissues0.00134% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/10766427/
8-oxo-GBreast cancer tissues.0.00207% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/10766427/
8-oxo-GHuman leukocytes0.00153% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/10656286/
8-oxo-GLung tumors0.00077% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/10657953/
8-oxo-GNormal lung tissues0.00081% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/10657953/
8-oxo-GMouse liver nDNA0.000032% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/11353081/
8-oxo-GMouse liver mtDNA0.000194% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/11353081/
8-oxo-GMouse brain nDNA0.000015% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/11353081/
8-oxo-GMouse brain mtDNA0.000342% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/11353081/
8-oxo-GMouse heart nDNA0.00002% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/11353081/
8-oxo-GMouse heart mtDNA0.000324% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/11353081/
8-oxo-GHCC peritumoral0.018% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/11680593/
8-oxo-GHCC tumor0.0032% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/11680593/
8-oxo-GNon-HCC peritumoral0.0039% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/11680593/
8-oxo-GNon-HCC tumor0.0108% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/11680593/
8-oxo-GNormal Human lymphocytes0.00098% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/11498287/
8-oxo-GAtherosclerotic patient Human lymphocytes0.001278% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/11498287/
8-oxo-GPig live0.001048% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/12507938/
8-oxo-GHeLa cells0.000523% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/12507938/
8-oxo-GHeLa cells0.000079% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/12507938/
8-oxo-GLymphocyte cell line0.00005% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/12419840/
8-oxo-GHeLa cells0.00401% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/12684094/
8-oxo-GLarynx tumor0.00195% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/12688418/
8-oxo-GLarynx adjacent tissues0.00205% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/12688418/
8-oxo-GFibroblast cell line0.00005% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/15190073/
8-oxo-GHuman leukocytes0.00031% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/15161827/
8-oxo-GKidney tissue0.1079% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/15533518/
8-oxo-GCultured cells0.00003% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/15613792/
8-oxo-GMouse brain cortices0.002219% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/15126047/
8-oxo-GHeLa cells0.00004% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/14990355/
8-oxo-GHuman lymphocytes0.000424% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/15533950/
8-oxo-GHuman lymphocyte0.000373% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/15533950/
8-oxo-GHeLa cells0.000278% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/15533950/
8-oxo-GHeLa cells0.00005% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/15533950/
8-oxo-GCD4+ T-cells0.004% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/15705786/
8-oxo-GNormal tissue, lung cancer patients0.001% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/15741575/
8-oxo-GMononucleocytes0.00049% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/15875808/
8-oxo-GHuman leukocytes0.0006% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/15523686/
8-oxo-GHuman lymphocytes0.00002% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/16983997/
8-oxo-GHuman leukocytes0.00048% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/17115893/
8-oxo-GHuman leukocytes0.0012% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/17543886/
8-oxo-GmESCs0.0005% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/24838012/
8-oxo-GPig liver,0.00013% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/24055867/
8-oxo-GPig brain0.00012% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/24055867/
8-oxo-GEscherichia coli0.00081% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/24055867/
8-oxo-GMouse lungs0.0042% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/25529473/
8-oxo-GRetinal pigment epithelium mtDNA0.017% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/26979577/
8-oxo-GRetinal pigment epithelium nuclear DNA0.000054% [8-oxo-G /dN)https://pubmed.ncbi.nlm.nih.gov/26979577/
8-oxo-GHepG2 cells0.00022% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/27416319/
8-oxo-GT24 cells0.00113% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/27416319/
8-oxo-GSprague-Dawley rat hepatic0.000265% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/27436759/
8-oxo-GNewborn mice brain tissues1.2% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/28501220/
8-oxo-GCHO_APP_iMTH1 cells.0.000653% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/29610342/
8-oxo-GMCF10A cells,0.00025% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/30462294/
8-oxo-GMCF10A cells,0.00025% [8-oxo-G /dG)https://pubmed.ncbi.nlm.nih.gov/30462294/
Modification Enzymes and Reactions
Modification Enzymes:reactive oxygen species
Reference:https://pubmed.ncbi.nlm.nih.gov/25008760/











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